Learning from Neurodiversity and 'Immaturity' to unveil Hidden Potentials: Rethinking Mental Health Research with Dr. Christian Beste

Learning from Neurodiversity and ‘Immaturity’ to unveil Hidden Potentials: Dr. Christian Beste about rethinking Mental Health Research

Science is about continuously questioning set knowledge. For this, different perspectives must be taken to get to the fundaments of things. Understanding how people control and select their actions requires looking at what is commonly seen as the “extreme ends” – as seen in neuropsychiatric disorders such as people with Addictions, ADHD, Tourette Syndrome, Movement Disorders, etc., but also in “immature” individuals such as children and adolescents. These groups provide different perspectives to the understanding of the fundaments of human action. The direct link between clinical and basic research creates complementary momentum as part of the psychological neuroscience approach, and translational insights into the nature of the cognitive functions under investigation. Through this, links between fields emerge.

Dr. Christian Beste started his research career out of a deep sense of dissatisfaction with how psychological and neuroscientific findings are used in the clinic to contribute to the diagnosis and clinical care of patients. It is not only the problem that the last 20 to 30 years of scientific knowledge gain have not yet entered clinical neuropsychological practice. It is also that a deficit-oriented view is still prevalent in neurology and psychiatry. This view is also dominating societal perceptions of these mental health conditions and “immaturity,” and research is hence mostly driven by a super-ordinate impetus of scientists to “learn about” these conditions characterized by deficiencies. “Learning about” is necessary, but insufficient to understand these conditions.

“Learning from” these conditions is complementary and advocates neurodiversity, which overcomes the deficit-oriented perspective on mental disorder and immaturity. It emerges from Dr. Christian Beste’s concept of psychological neuroscience and provides an opportunity to think into unconventional directions one may not dare to think of: Are there hidden potentials in disorders? There are many lines of evidence that this is the case, necessitating a shift in societal views through knowledge transfer in terms of neurodiversity, but also raising science political aspects. These, on the one hand, drive Dr. Christian Beste’s research agenda, and have strong political implications.

Dr. Christian Beste about the political importance of a Psychological Neuroscience of Neurodiversity

I.

In recent years, there has been a growing recognition of the need to rethink our approach to mental health research. This is motivated by studies that emphasize the similarities between individuals with mental health issues and the general population. This approach, which advocates for funding research that challenges traditional perceptions of mental health, aims to foster a more inclusive and holistic understanding of mental health conditions. By focusing on commonalities rather than differences, researchers can contribute to a more nuanced view of mental health, breaking down long-standing stigmas and misconceptions.

Dr. Christian Beste about the political importance of a Psychological Neuroscience of Neurodiversity
II.

Another significant shift in the mental health research paradigm is the support of approaches reflecting psychological neuroscience calling for the integration of theoretical predictions with practical research applications. By urging the adoption of funding policies that back such a psychological neuroscience, we can ensure that mental health research is not only theoretically sound but also practically relevant and ready for knowledge transfer. The close connection between psychological neuroscience and knowledge transfer is crucial for developing effective treatments and interventions that can make a real difference in the lives of those affected by mental health issues.

IV.

Reframing mental health perspectives is vital in changing societal attitudes through knowledge transfer. There’s a need to shift the focus from viewing mental health issues in terms of deficiencies to recognizing and valuing the abilities and strengths of those affected. By changing how society views mental health, we can create a more inclusive and supportive environment for everyone. This perspective ensures that the benefits of mental health research extend beyond the scientific community, says Dr. Christian Beste, reaching out to the wider society by improving public understanding of mental health, reducing stigma, and enhancing support systems for those affected.

III.

The focus on psychological neuroscience outcomes is also paramount. Emphasizing the importance of funding research grounded in strong theoretical frameworks is essential to ensure the relevance and depth of findings. When mental health research is underpinned by robust theoretical foundations, as brought with psychological neuroscience, it stands a better chance of obtaining results that are not only scientifically valid but also meaningful and applicable in real-world scenarios. This approach can lead to breakthroughs that significantly improve our understanding and treatment of mental health conditions.

Example papers:

Rethinking Movement Disorders.

Münchau, A., Klein, C. and Beste, C. 2024 Jan; Mov Disord. 2024 Jan 9. doi: 10.1002/mds.29706. Epub ahead of print. PMID: 38196315.

Beste C, Moll CKE, Pötter-Nerger M, Münchau A.Trends Cogn Sci. 2018 Sep;22(9):747-751. doi: 10.1016/j.tics.2018.06.007. Epub 2018 Jul 14.PMID: 30017252 Review.

Kleimaker M, Takacs A, Conte G, Onken R, Verrel , Bäumer T, Münchau A, Beste C.Brain. 2020 Jun 1;143(6):1934-1945. doi: 10.1093/brain/awaa111.PMID: 32464659

Beste C, Humphries M, Saft C.Neuroimage Clin. 2014 Apr 12;4:623-34. doi: 10.1016/j.nicl.2014.04.003. eCollection 2014.PMID: 24936413 

Beste C, Wascher E, Dinse HR, Saft C.Curr Biol. 2012 Oct 23;22(20):1914-7. doi: 10.1016/j.cub.2012.08.012. Epub 2012 Sep 13.PMID: 22981772 

Beste C.Front Hum Neurosci. 2022 Nov 30;16:1054714. doi: 10.3389/fnhum.2022.1054714. eCollection 2022.PMID: 36530201

Bartha S, Bluschke A, Rawish T, Naumann KER, Wendiggensen P, Bäumer T, Roessner V, Münchau A, Beste C.Ann Neurol. 2023 Mar;93(3):472-478. doi: 10.1002/ana.26586. Epub 2023 Jan 18.PMID: 36565297